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1

New Efficient Synthesis of Resorcinylic Macrolides via Ynolides: Establishment of Cycloproparadicicol as Synthetically Feasible Preclinical Anticancer Agent Based on Hsp90 as the Target

Yang, Zhi-Qiang, Geng, Xudong, Solit, David, Pratilas, Christine A., Rosen, Neal, Danishefsky, Samuel J.

Journal:

Journal of the American Chemical Society

Year:

2004

Language:

english

File:

PDF, 279 KB

english, 2004

2

Is high use of caesarean section sometimes justified?

Pratilas, Georgios C, Sotiriadis, Alexandros, Dinas, Konstantinos

Journal:

Lancet (London, England)

Year:

2019

Language:

english

File:

PDF, 202 KB

english, 2019

3

Metanephric Adenoma–Epithelial Wilms Tumor Overlap Lesions

Wobker, Sara E., Matoso, Andres, Pratilas, Christine A., Mangray, Shamlal, Zheng, Gang, Lin, Ming-Tseh, Debeljak, Marija, Epstein, Jonathan I., Argani, Pedram

Journal:

American Journal of Surgical Pathology

Year:

2019

File:

PDF, 1.79 MB

2019

4

Cervical, anal and oral HPV detection and HPV type concordance among women referred for colposcopy

Nasioutziki, Maria, Chatzistamatiou, Kimon, Loufopoulos, Panagiotis-Dimitrios, Vavoulidis, Eleftherios, Tsampazis, Nikolaos, Pratilas, George-Chrysostomos, Liberis, Anastasios, Karpa, Vasiliki, Parcha

Journal:

Infectious Agents and Cancer

Year:

2020

File:

PDF, 535 KB

2020

5

New Efficient Synthesis of Resorcinylic Macrolides via Ynolides: Establishment of Cycloproparadicicol as Synthetically Feasible Preclinical Anticancer Agent Based on Hsp90 as the Target.

Zhi-Qiang Yang, Xudong Geng, David Solit, Christine A. Pratilas, Neal Rosen, Samuel J. Danishefsky

Journal:

Year:

2004

File:

PDF, 11 KB

2004

6

The effect of halothane anaesthesia on liver regeneration

Vasilios Pratilas, Margaret G. Pratila, John P. Bramis

Journal:

Canadian Journal of Anesthesia/Journal canadien d'anesthésie

Year:

1978

Language:

english

File:

PDF, 494 KB

english, 1978

7

Anaesthetic management of phaeochromocytoma

Vasilios Pratilas, Margaret G. Pratila

Journal:

Canadian Journal of Anesthesia/Journal canadien d'anesthésie

Year:

1979

Language:

english

File:

PDF, 466 KB

english, 1979

8

Propofol infusion in Carcinoid Syndrome

Margaret G. Pratila, Vasilios Pratilas

Journal:

Canadian Journal of Anesthesia/Journal canadien d'anesthésie

Year:

1991

Language:

english

File:

PDF, 191 KB

english, 1991

9

Anaesthetic considerations in the prolonged Q-T interval (LQTS): A case report

Sidney Owitz, Vasilios Pratilas, Margaret G. Pratila, Ivan Dimich

Journal:

Canadian Journal of Anesthesia/Journal canadien d'anesthésie

Year:

1979

Language:

english

File:

PDF, 1.30 MB

english, 1979

10

A case of tachydysrhythmia : Refractory to propranolol and responsive to neostigmine

MARGARET G. PRATILA, VASILIOS PRATILAS

Journal:

Year:

1977

Language:

english

File:

PDF, 225 KB

english, 1977

11

BRAF mutation predicts sensitivity to MEK inhibition

Solit, David B., Garraway, Levi A., Pratilas, Christine A., Sawai, Ayana, Getz, Gad, Basso, Andrea, Ye, Qing, Lobo, Jose M., She, Yuhong, Osman, Iman

Journal:

Year:

2005

Language:

english

File:

PDF, 530 KB

english, 2005

12

Sympathetic Nervous System Tonicity and Post-Coronary Artery Bypass Hypertension

V. Pratilas, M. G. Pratija, N. D. Vlachakis, S. Owitz, I. Dimich

Journal:

Acta Anaesthesiologica Scandinavica

Year:

1980

Language:

english

File:

PDF, 454 KB

english, 1980

13

Reactivation of ERK Signaling Causes Resistance to EGFR Kinase Inhibitors

Ercan, D., Xu, C., Yanagita, M., Monast, C. S., Pratilas, C. A., Montero, J., Butaney, M., Shimamura, T., Sholl, L., Ivanova, E. V., Tadi, M., Rogers, A., Repellin, C., Capelletti, M., Maertens, O., G

Journal:

Cancer Discovery

Year:

2012

Language:

english

File:

PDF, 1.67 MB

english, 2012

14

Identification of Unique MEK-Dependent Genes in GNAQ Mutant Uveal Melanoma Involved in Cell Growth, Tumor Cell Invasion, and MEK Resistance

Ambrosini, G., Pratilas, C. A., Qin, L.-X., Tadi, M., Surriga, O., Carvajal, R. D., Schwartz, G. K.

Journal:

Clinical Cancer Research

Year:

2012

Language:

english

File:

PDF, 1.36 MB

english, 2012

15

Relief of Profound Feedback Inhibition of Mitogenic Signaling by RAF Inhibitors Attenuates Their Activity in BRAFV600E Melanomas

Piro Lito, Christine A. Pratilas, Eric W. Joseph, Madhavi Tadi, Ensar Halilovic, Matthew Zubrowski, Alan Huang, Wai Lin Wong, Margaret K. Callahan, Taha Merghoub, Jedd D. Wolchok, Elisa de Stanchina,

Journal:

Year:

2012

Language:

english

File:

PDF, 2.16 MB

english, 2012

16

553 POSTER B-RAF mutation is associated with altered patterns of negative feedback of MAPK signaling that correlate with increased output of the pathway and increased sensitivity to MEK inhibition

C. Pratilas, H. Zhao, A. Viale, D. Solit, N. Rosen

Journal:

European Journal of Cancer Supplements

Year:

2006

Language:

english

File:

PDF, 53 KB

english, 2006

17

Concurrent loss of the PTEN and RB1 tumor suppressors attenuates RAF dependence in melanomas harboring V600EBRAF

Xing, F, Persaud, Y, Pratilas, C A, Taylor, B S, Janakiraman, M, She, Q-B, Gallardo, H, Liu, C, Merghoub, T, Hefter, B, Dolgalev, I, Viale, A, Heguy, A, De Stanchina, E, Cobrinik, D, Bollag, G, Wolcho

Journal:

Year:

2012

Language:

english

File:

PDF, 849 KB

english, 2012

18

Genomic and Biological Characterization of Exon 4 KRAS Mutations in Human Cancer

Janakiraman, M., Vakiani, E., Zeng, Z., Pratilas, C. A., Taylor, B. S., Chitale, D., Halilovic, E., Wilson, M., Huberman, K., Ricarte Filho, J. C., Persaud, Y., Levine, D. A., Fagin, J. A., Jhanwar, S

Journal:

Cancer Research

Year:

2010

Language:

english

File:

PDF, 1.22 MB

english, 2010

19

Sick sinus syndrome in a teenager treated with idarubicin

Pratila, Margaret G., Steinherz, Laurel J., Pratilas, Vasilios

Journal:

Journal of Cardiothoracic and Vascular Anesthesia

Year:

1993

Language:

english

File:

PDF, 395 KB

english, 1993

20

Cardiovascular effects of a nifedipine infusion during fentanyl-nitrous oxide anesthesia in dogs

Griffin, Richard M., Dimich, Ivan, Jurado, Roy, Pratilas, Vasilios, Shiang, Howard, Fagerstrom, Richard, Kaplan, Joel A.

Journal:

Journal of Cardiothoracic Anesthesia

Year:

1989

Language:

english

File:

PDF, 584 KB

english, 1989

21

Appointments.

Griffin, Richard M., Dimich, Ivan, Jurado, Roy, Pratilas, Vasilios, Shiang, Howard, Fagerstrom, Richard, Kaplan, Joel A.

Journal:

Year:

1896

Language:

english

File:

PDF, 208 KB

english, 1896

22

Software survey section

Griffin, Richard M., Dimich, Ivan, Jurado, Roy, Pratilas, Vasilios, Shiang, Howard, Fagerstrom, Richard, Kaplan, Joel A.

Journal:

Year:

1985

Language:

english

File:

PDF, 135 KB

english, 1985

23

Propofol versus midazolam for monitored sedation: a comparison of intraoperative and recovery parameters

Fischer, Mary E, Pratila, Margaret G, Alagesan, Rita, Alagesan, Ramdas, Reinsel, Ruth A, Pratilas, David

Journal:

Journal of Clinical Anesthesia

Year:

1993

Language:

english

File:

PDF, 928 KB

english, 1993

24

V.02.2 ROLE OF ENDOSCOPY IN PREVENTION OF LEAKS AFTER LAPAROSCOPIC SLEEVE GASTRECTOMY

Rossetti, G., Marra, T., Napoletano, D., Moccia, F., Cimmino, M., Romano, G., Bondanese, M.C., Pascotto, B., Buonomo, M., Pratilas, M., Fei, L.

Journal:

Digestive and Liver Disease

Year:

2014

Language:

english

File:

PDF, 666 KB

english, 2014

25

Outcome of medical and surgical therapy of GERD: Predictive role of quality of life scores and instrumental evaluation

Rossetti, Gianluca, Limongelli, Paolo, Cimmino, Marco, Napoletano, Domenico, Bondanese, Maria Chiara, Romano, Giovanni, Pratilas, Manousos, Guerriero, Ludovica, Orlando, Francesco, Conzo, Giovanni, Am

Journal:

International Journal of Surgery

Year:

2014

Language:

english

File:

PDF, 241 KB

english, 2014

26

Genetic Predictors of MEK Dependence in Non-Small Cell Lung Cancer

Pratilas, C. A., Hanrahan, A. J., Halilovic, E., Persaud, Y., Soh, J., Chitale, D., Shigematsu, H., Yamamoto, H., Sawai, A., Janakiraman, M., Taylor, B. S., Pao, W., Toyooka, S., Ladanyi, M., Gazdar,

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 576 KB

english, 2008

27

The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner

Eric W. Joseph, Christine A. Pratilas, Poulikos I. Poulikakos, Madhavi Tadi, Weiqing Wang, Barry S. Taylor, Ensar Halilovic, Yogindra Persaud, Feng Xing, Agnes Viale, James Tsai, Paul B. Chapman, Gide

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.76 MB

english, 2010

28

The Rho GTPase Rnd1 suppresses mammary tumorigenesis and EMT by restraining Ras-MAPK signalling

Okada, Tomoyo, Sinha, Surajit, Esposito, Ilaria, Schiavon, Gaia, López-Lago, Miguel A., Su, Wenjing, Pratilas, Christine A., Abele, Cristina, Hernandez, Jonathan M., Ohara, Masahiro, Okada, Morihito,

Journal:

Nature Cell Biology

Year:

2014

Language:

english

File:

PDF, 6.00 MB

english, 2014

29

Ifosfamide dose-intensification for patients with metastatic Ewing sarcoma

Magnan, Heather, Goodbody, Christine M., Riedel, Elyn, Pratilas, Christine A., Wexler, Leonard H., Chou, Alexander J.

Journal:

Pediatric Blood & Cancer

Year:

2015

Language:

english

File:

PDF, 374 KB

english, 2015

30

Interferon α/β Enhances the Cytotoxic Response of MEK Inhibition in Melanoma

Litvin, Oren, Schwartz, Sarit, Wan, Zhenmao, Schild, Tanya, Rocco, Mark, Oh, Nul Loren, Chen, Bo-Juen, Goddard, Noel, Pratilas, Christine, Pe’er, Dana

Journal:

Year:

2015

Language:

english

File:

PDF, 3.99 MB

english, 2015

31

The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner

Joseph, E. W., Pratilas, C. A., Poulikakos, P. I., Tadi, M., Wang, W., Taylor, B. S., Halilovic, E., Persaud, Y., Xing, F., Viale, A., Tsai, J., Chapman, P. B., Bollag, G., Solit, D. B., Rosen, N.

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.11 MB

english, 2010

32

V600EBRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway

Pratilas, C. A., Taylor, B. S., Ye, Q., Viale, A., Sander, C., Solit, D. B., Rosen, N.

Journal:

Proceedings of the National Academy of Sciences

Year:

2009

Language:

english

File:

PDF, 829 KB

english, 2009

33

Targeting the Mitogen-Activated Protein Kinase Pathway: Physiological Feedback and Drug Response

Pratilas, C. A., Solit, D. B.

Journal:

Clinical Cancer Research

Year:

2010

Language:

english

File:

PDF, 555 KB

english, 2010

34

Loss of NF1 in Cutaneous Melanoma Is Associated with RAS Activation and MEK Dependence

Nissan, M. H., Pratilas, C. A., Jones, A. M., Ramirez, R., Won, H., Liu, C., Tiwari, S., Kong, L., Hanrahan, A. J., Yao, Z., Merghoub, T., Ribas, A., Chapman, P. B., Yaeger, R., Taylor, B. S., Schultz

Journal:

Cancer Research

Year:

2014

Language:

english

File:

PDF, 1.07 MB

english, 2014

35

On Mesmerism*

Pratila, Margaret G.

Journal:

Bulletin of Anesthesia History

Year:

2002

Language:

english

File:

PDF, 326 KB

english, 2002

36

3'-Deoxy-3'-[18F]Fluorothymidine Positron Emission Tomography Is a Sensitive Method for Imaging the Response of BRAF-Dependent Tumors to MEK Inhibition

Solit, D. B., Santos, E., Pratilas, C. A., Lobo, J., Moroz, M., Cai, S., Blasberg, R., Sebolt-Leopold, J., Larson, S., Rosen, N.

Journal:

Cancer Research

Year:

2007

Language:

english

File:

PDF, 550 KB

english, 2007

37

Paradoxical Activation of T Cells via Augmented ERK Signaling Mediated by a RAF Inhibitor

Callahan, M. K., Masters, G., Pratilas, C. A., Ariyan, C., Katz, J., Kitano, S., Russell, V., Gordon, R. A., Vyas, S., Yuan, J., Gupta, A., Wigginton, J. M., Rosen, N., Merghoub, T., Jure-Kunkel, M.,

Journal:

Cancer Immunology Research

Year:

2014

Language:

english

File:

PDF, 1.19 MB

english, 2014

38

Combined EGFR/MEK Inhibition Prevents the Emergence of Resistance in EGFR mutant Lung Cancer

Tricker, E. M., Xu, C., Uddin, S., Capelletti, M., Ercan, D., Ogino, A., Pratilas, C. A., Rosen, N., Gray, N. S., Wong, K.-K., Janne, P. A.

Journal:

Cancer Discovery

Year:

2015

Language:

english

File:

PDF, 1.21 MB

english, 2015

39

Transcriptional Pathway Signatures Predict MEK Addiction and Response to Selumetinib (AZD6244)

Dry, J. R., Pavey, S., Pratilas, C. A., Harbron, C., Runswick, S., Hodgson, D., Chresta, C., McCormack, R., Byrne, N., Cockerill, M., Graham, A., Beran, G., Cassidy, A., Haggerty, C., Brown, H., Ellis

Journal:

Cancer Research

Year:

2010

Language:

english

File:

PDF, 973 KB

english, 2010

40

Perturbation Biology: Inferring Signaling Networks in Cellular Systems

Molinelli, Evan J., Korkut, Anil, Wang, Weiqing, Miller, Martin L., Gauthier, Nicholas P., Jing, Xiaohong, Kaushik, Poorvi, He, Qin, Mills, Gordon, Solit, David B., Pratilas, Christine A., Weigt, Mart

Journal:

PLoS Computational Biology

Year:

2013

Language:

english

File:

PDF, 2.17 MB

english, 2013

41

BRAF V600E Mutation Is Associated with Preferential Sensitivity to Mitogen-Activated Protein Kinase Kinase Inhibition in Thyroid Cancer Cell Lines

Leboeuf, Rebecca, Baumgartner, Jacqueline E., Benezra, Miriam, Malaguarnera, Roberta, Solit, David, Pratilas, Christine A., Rosen, Neal, Knauf, Jeffrey A., Fagin, James A.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2008

Language:

english

File:

PDF, 334 KB

english, 2008

42

The Hepatoprotective Effect of Oxygen During Haiothane Anesthesia

PRATILAS, VASILIOS, PRATILA, MARGARET G., BRAMIS, JOHN, SMITH, HARRY

Journal:

Anesthesia & Analgesia

Year:

1978

Language:

english

File:

PDF, 396 KB

english, 1978

43

A Comparative Study Between a Calcium Channel Blocker (Nicardipine) and a Combined ??-??-Blocker (Labetalol) for the Control of Emergence Hypertension During Craniotomy for Tumor Surgery

Kross, Ronald A., Ferri, Enrico, Leung, Denis, Pratila, Margaret, Broad, Clara, Veronesi, Michele, Melendez, Jose A.

Journal:

Anesthesia & Analgesia

Year:

2000

Language:

english

File:

PDF, 119 KB

english, 2000

44

A12 Therapeutic Role of Esmolol in Perioperative Hypertension in Ambulatory Surgery

Dimich, I., Singh, P., Sampson, I., Pratilas, V., Sonnenklar, N.

Journal:

Year:

1990

File:

PDF, 82 KB

1990

45

A1114 ANESTHESIA FOR PEDIATRIC CANCER PATIENTS

Barst, S, McDowall, R, Pratila, M, Scher, C, Shah, S, Alagesan, R, Lafourcade, G, Poremba, F

Journal:

Year:

1990

File:

PDF, 87 KB

1990

46

Dermatologic adverse events in pediatric patients receiving targeted anticancer therapies: A pooled analysis

Belum, Viswanath Reddy, Washington, Courtney, Pratilas, Christine A., Sibaud, Vincent, Boralevi, Franck, Lacouture, Mario E.

Journal:

Pediatric Blood & Cancer

Year:

2015

Language:

english

File:

PDF, 529 KB

english, 2015

47

Epidermolysis Bullosa Manifested and Treated during Anesthesia

PRATILAS, VASILIOS, BIEZUNSKI, ARTHUR

Journal:

Year:

1975

File:

PDF, 163 KB

1975

48

CELLULAR MECHANISMS OF CARDIAC ARRHYTHMIAS INDUCED BY BUPIVACAINE

Wojtczak, J. A., Pratilas, V., Griffin, R. M., Kaplan, J. A.

Journal:

Year:

1984

File:

PDF, 101 KB

1984

49

CARDIOVASCULAR EFFECTS OF NIFEDIPINE INFUSION DURING FENTANYL ANESTHESIA

Griffin, R M, Dimich, I, Jurado, R, Pratilas, V, Kaplan, J A, Fagerstrom, R

Journal:

Year:

1984

File:

PDF, 80 KB

1984

50

Unexplained Brachial-plexus Palsy

ADELMAN, MILTON, PRATILAS, VASILIOS

Journal:

Year:

1979

File:

PDF, 164 KB

1979